Anti-Human/Mouse/Rat Claudin 7 Polyclonal Antibody

Claudin 7多克隆抗体

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Differential expression of this gene has been observed in different types of malignancies, including breast cancer, ovarian cancer, hepatocellular carcinomas, urinary tumors, prostate cancer, lung cancer, head and neck cancers, thyroid carcinomas, etc.. Alternatively spliced transcript variants encoding different isoforms have been found.
价格: 2507.4元
  • Buy 5 for ¥2382.03 each and save 5%
  • Buy 21 for ¥2256.66 each and save 10%
  • Buy 31 for ¥2131.29 each and save 15%
  • Buy 51 for

基本信息

数据文档 查看数据文档
货号 PA11221
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CLDN7
特异性 Expressed in kidney, lung and prostate. Isoform 1 seems to be predominant, except in some normal prostate samples, where isoform 2 is the major form. Down-regulated in breast cancers, including ductal carcinoma in situ (DCIS), lobular carcinoma in situ (LCIS) and invasive ductal carcinoma (IDC) (at protein level), as well as in several cancer cell lines. Loss of expression correlates with histological grade, occurring predominantly in high-grade lesions.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O95471
浓度 0.3 mg/mL
推荐稀释度 WB 1:1000-1:3000, IHC 1:50-1:150
配方
应用范围 WB,IHC,ELISA
别名 CEPTR L2,CEPTRL 2,CEPTRL2,Claudin 1,Claudin 9,Claudin-7,Claudin1,Claudin7,Claudin9,CLD7,CLDN 7,CLDN-7,CLDN7,Clostridium perfringens enterotoxin receptor like 2,CPETR L2,CPETRL 2,CPETRL2,Hs.84359
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

©2024 武汉天正源生物科技有限公司版权所有. SiteMap