Anti-Human/Mouse/Rat CD10 Polyclonal Antibody

CD10多克隆抗体

This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. 
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基本信息

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货号 PA10406
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human MME
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P08473
浓度 0.5 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 Atriopeptidase,CALLA,CD10,CD10 antigen,Common acute lymphocytic leukemia antigen,DKFZp686O16152,EC 3.4.24.11,Enkephalinase,EPN,Membrane metallo endopeptidase (neutral endopeptidase,enkephalinase),Membrane metallo endopeptidase (neutral endopeptidase,enkephalinase,CALLA,CD10),Membrane metallo endopeptidase,Membrane metallo endopeptidase variant 1,Membrane metallo endopeptidase variant 2,Membrane metalloendopeptidase,Membrane metalloendopeptidase neutral endopeptidase enkephalinase,Membrane metalloendopeptidase neutral endopeptidase enkephalinase CALLA CD10,Membrane metalloendopeptidase variant 1,Membrane metalloendopeptidase variant 2,MGC126681,MGC126707,MME,NEP,NEP,Neprilysin,neprilysin-390,neprilysin-411,Neutral endopeptidase 24.11,Neutral endopeptidase,Neutral endopeptidase,membrane-associated,SFE,Skin fibroblast elastase
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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