Anti-Human/Mouse/Rat CAV1 Polyclonal Antibody

CAV1多克隆抗体

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
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基本信息

数据文档 查看数据文档
货号 PA09378
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CAV1
特异性 Expressed in muscle and lung, less so in liver, brain and kidney.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q03135
浓度 0.5 mg/mL
推荐稀释度 WB 1:1000-1:5000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 BSCL3,CAV,CAV1,CAV1,caveolae protein,22 kD,caveolin 1 alpha isoform,caveolin 1 beta isoform,Caveolin 1 caveolae protein 22kDa,Caveolin-1,Caveolin1,cell growth-inhibiting protein 32,CGL3,LCCNS,MSTP085,OTTHUMP00000025031,PPH3,VIP 21,VIP21
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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