Anti-Human/Mouse/Rat Cadherin-7 Polyclonal Antibody

Cadherin-7多克隆抗体

This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium dependent cell-cell adhesion molecule is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types. Mutations in this gene may be associated with bipolar disease in human patients. This gene is present in a gene cluster on chromosome 18.CDH7 (Cadherin 7) is a Protein Coding gene. Among its related pathways are Cell junction organization and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CDH20.
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基本信息

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货号 PA02391
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human Cadherin-7
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q9ULB5
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
配方
应用范围 WB,IHC-p,IF,ELISA
别名 Cadherin 7 type 2,Cadherin7,CDH 7,CDH7,CDH7L1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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