Anti-Human/Mouse/Rat ATP7B Polyclonal Antibody

ATP7B多克隆抗体

This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). 
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基本信息

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货号 PA02726
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human ATP7B
特异性 Most abundant in liver and kidney and also found in brain. Isoform 2 is expressed in brain but not in liver. The cleaved form WND/140 kDa is found in liver cell lines and other tissues.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P35670
浓度 0.4 mg/mL
推荐稀释度 IHC 1:25-100, ELISA 1:2000-5000
配方
应用范围 IHC,ELISA
别名 WD,PWD,WC1,WND
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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