Anti-Human/Mouse/Rat ATM Monoclonal Antibody

ATM单克隆抗体

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.
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基本信息

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货号 MA02733
规格 100μl
宿主 Mouse
免疫原 Recombinant Protein of ATM of ATM
特异性 Found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes.
亚型 IgG
反应性 Human,Mouse,Rat
克隆 3D3
Uniprot Q13315
浓度 1mg/mL
推荐稀释度 IHC 1:100-200
配方
应用范围 IHC-p
别名 A-T mutated,A-T mutated homolog,AT mutated,AT1,ATA,Ataxia telangiectasia mutated,Ataxia telangiectasia mutated gene,Ataxia telangiectasia mutated homolog (human),Ataxia telangiectasia mutated homolog,ATC,ATD,ATDC,ATE,ATM,ATM serine/threonine kinase,ATM,DKFZp781A0353,MGC74674,OTTHUMP00000232981,Serine protein kinase ATM,Serine-protein kinase ATM,Serine/threonine-protein kinase ATM,Tefu,TEL1,TEL1,telomere maintenance 1,homolog,TELO1,Telomere fusion protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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