Anti-Human/Mouse/Rat ALOX5 Polyclonal Antibody

ALOX5多克隆抗体

This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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基本信息

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货号 PA11379
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human ALOX5
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P09917
浓度 0.6 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 5 LO,5 LOX,5-lipoxygenase,5-LO,5-LOX,5LOX,5LPG,ALOX 5,Alox5,Arachidonate 5 lipoxygenase,Arachidonate 5-lipoxygenase,arachidonic 5-lipoxygenase alpha-10 isoform,arachidonic 5-lipoxygenase delta-10-13 isoform,arachidonic 5-lipoxygenase delta-13 isoform,arachidonic 5-lipoxygenase delta-p10 isoform,Arachidonic acid 5 lipoxygenase,Leukotriene A4 synthase,LOG 5,LOG5,LOX5,MGC163204
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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