Anti-Human/Mouse/Rat ALDOB Polyclonal Antibody

ALDOB多克隆抗体

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.
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基本信息

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货号 PA09993
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human ALDOB
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P05062
浓度 0.6 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 ALDB,ALDO B,ALDO2,ALDOB,ALDOB,Aldolase 2,Aldolase B,Aldolase B fructose bisphosphate,Aldolase2,AldolaseB,EC 4.1.2.13,Fructose bisphosphate aldolase B,Fructose-bisphosphate aldolase B,Liver type aldolase,Liver-type aldolase,MS1077
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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