Anti-Human/Mouse/Rat AKT1 Monoclonal Antibody

AKT1单克隆抗体

The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1,which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with/without phospho- modification.
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基本信息

数据文档 查看数据文档
货号 MA01845
规格 100μl
宿主 Mouse
免疫原 Fusion protein of AKT1
特异性 Expressed in all human cell types so far analyzed. The Tyr-176 phosphorylated form shows a significant increase in expression in breast cancers during the progressive stages i.e. normal to hyperplasia (ADH), ductal carcinoma in situ (DCIS), invasive ductal carcinoma (IDC) and lymph node metastatic (LNMM) stages.
亚型 IgG1
反应性 Human,Mouse,Rat
克隆 405
Uniprot P31749
浓度 None
推荐稀释度 WB 1:1000-1:10000, IHC 1:100-1:400, IF 1:10-1:100
配方
应用范围 WB,IHC,IF,ELISA
别名 AKT 1,AKT,AKT1,AKT1,MGC99656,PKB,PKB-ALPHA,PRKBA,Protein Kinase B Alpha,Protein kinase B,Proto-oncogene c-Akt,RAC Alpha,RAC,RAC-alpha serine/threonine-protein kinase,RAC-PK-alpha
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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