Anti-Human/Mouse PTPN22 Polyclonal Antibody

PTPN22多克隆抗体

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described.
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基本信息

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货号 PA10303
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PTPN22
特异性 Predominantly expressed in lymphoid tissues and cells. Isoform 1 is expressed in thymocytes and both mature B and T-cells.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9Y2R2
浓度 0.2 mg/mL
推荐稀释度 IHC 1:30-1:150
配方
应用范围 IHC,ELISA
别名 Hematopoietic cell protein tyrosine phosphatase 70Z PEP,Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP,Lymphoid phosphatase,Lymphoid specific protein tyrosine phosphatase,lymphoid-specific,inducible human protein tyrosine phosphatase,Lyp 1,Lyp 2,LyP,Lyp1,Lyp2,LyPTP,OTTHUMP00000013720,OTTHUMP00000013721,OTTHUMP00000233450,OTTHUMP00000233451,PEP,PEST-domain phosphatase,Protein tyrosine phosphatase non receptor type 22 (lymphoid),Protein tyrosine phosphatase non receptor type 22,Protein tyrosine phosphatase non receptor type 8,Protein tyrosine phosphatase non receptor type 8,formerly,PTN22,PTPN 22,PTPN 8,Ptpn22,PTPN8,PTPN8,formerly,Tyrosine-protein phosphatase non-receptor type 22
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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