Anti-Human /Mouse PSME3 Polyclonal Antibody

PSME3多克隆抗体

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the gamma subunit of the 11S regulator. Six gamma subunits combine to form a homohexameric ring. Alternate splicing results in multiple transcript variants.
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基本信息

数据文档 查看数据文档
货号 PA02980
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PSME3
特异性
亚型 IgG
反应性 Human ,Mouse
克隆
Uniprot P61289
浓度 1 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-100
配方
应用范围 WB,IHC
别名 11S regulator complex gamma subunit,11S regulator complex subunit gamma,Activator of multicatalytic protease subunit 3,Ki,Ki antigen,Ki nuclear autoantigen,Ki,PA28 gamma,PA28 gamma,PA28g,PA28gamma,Proteasome (prosome,macropain) activator subunit 3 (PA28 gamma,Ki),Proteasome (prosome,macropain) activator subunit 3,Proteasome activator 28 gamma,Proteasome activator 28 subunit gamma,Proteasome activator complex subunit 3,Proteasome activator subunit 3,PSME3,PSME3,REG GAMMA,REG-gamma
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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