Anti-Human/Mouse PPP1R13L Polyclonal Antibody

PPP1R13L多克隆抗体

RelA-associated inhibitor is a protein that in humans is encoded by the PPP1R13L gene. Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis. Interacts with RELA NF-kappa-B subunit and with SP1 via its C-terminus part. Interacts with p53/TP53, TP63 and TP73.
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基本信息

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货号 PA07892
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human PPP1R13L
特异性 Highly expressed in heart, placenta and prostate. Weakly expressed in brain, liver, skeletal muscle, testis and peripheral blood leukocyte.1 Publication
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q8WUF5
浓度 0.7 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 IASPP,inhibitor of apoptosis stimulating protein of p53,Inhibitor of ASPP protein,NFkB interacting protein 1,NKIP1,PPP1R13B-like protein,PPP1R13L,Protein iASPP,protein phosphatase 1 regulatory (inhibitor) subunit 13 like,RAI,RelA-associated inhibitor
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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