Anti-Human/Mouse PIM2 Polyclonal Antibody

PIM2多克隆抗体

This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.
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基本信息

数据文档 查看数据文档
货号 PA12706
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PIM2
特异性 Highly expressed in hematopoietic tissues, in leukemic and lymphoma cell lines, testis, small intestine, colon and colorectal adenocarcinoma cells. Weakly expressed in normal liver, but highly expressed in hepatocellular carcinoma tissues.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9P1W9
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 OTTHUMP00000025825,Pim 2 oncogene,Pim 2h,Pim-2h,PIM2,PIM2 Oncogene,PIM2,Pim2h,Proto Oncogene PIM2,Proto-oncogene Pim-2 (serine threonine kinase),Serine/threonine kinase PIM2,Serine/threonine-protein kinase Pim-2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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