Anti-Human/Mouse/Monkey GPR132 Polyclonal Antibody

GPR132多克隆抗体

This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants.GPR132 (G Protein-Coupled Receptor 132) is a Protein Coding gene. Diseases associated with GPR132 include Inclusion Conjunctivitis. Among its related pathways are RET signaling and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is GPR4.
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基本信息

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货号 PA04105
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human G2A
特异性 Highly expressed in macrophages and hematopoietic tissues rich in lymphocytes, like spleen and thymus. Weakly expressed in heart and lung. In atherosclerotic plaques, expression is observed around the lipid core and at the shoulder region.
亚型 IgG
反应性 Human,Mouse,Monkey
克隆
Uniprot Q9UNW8
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
配方
应用范围 WB,IF,ELISA
别名 G Protein Coupled Receptor G2A,G2 accumulation protein,G2A,GP132,GPR132,Probable G-protein coupled receptor 132
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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