Anti-Human/Mouse MCM4 Polyclonal Antibody

MCM4多克隆抗体

The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 6 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of this protein by CDC2 kinase reduces the DNA helicase activity and chromatin binding of the MCM complex. This gene is mapped to a region on the chromosome 8 head-to-head next to the PRKDC/DNA-PK, a DNA-activated protein kinase involved in the repair of DNA double-strand breaks. Alternatively spliced transcript variants encoding the same protein have been reported.
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基本信息

数据文档 查看数据文档
货号 PA10970
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human MCM4
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P33991
浓度 0.3 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 19G,AI325074,AU045576,CDC 21,CDC 54,CDC21,CDC21 homolog,CDC21,S. pombe,homolog of,CDC54,Cell division cycle 21,S. pombe,homolog of,DNA replication licensing factor MCM 4,DNA replication licensing factor MCM4,hCdc 21,hCdc21,Homolog of S. pombe cell devision cycle 21,KIAA4003,mcdc21,MCM 4,MCM 4 minichromosome maintenance deficient 4,mcm4,MCM4 minichromosome maintenance deficient 4,MCM4 minichromosome maintenance deficient 4,mitotin (S. cerevisiae),MCM4,Mcmd4,MGC33310,Minichromosome maintenance 4,Minichromosome maintenance complex component 4,Minichromosome maintenance deficient (S. cerevisiae) 4,Minichromosome maintenance deficient 4,Minichromosome maintenance deficient 4 homolog (S. cerevisiae),Minichromosome maintenance,S. cerevisiae,homolog of,4,mKIAA4003,NKCD,NKGCD,P1 CDC21,P1-CDC21,P1CDC21
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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