Anti-Human/Mouse MAP3K5 Polyclonal Antibody

MAP3K5多克隆抗体

Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells; MAPKKK5 does not activate MAPK/ERK.
价格: 2507.4元
  • Buy 5 for ¥2382.03 each and save 5%
  • Buy 21 for ¥2256.66 each and save 10%
  • Buy 31 for ¥2131.29 each and save 15%
  • Buy 51 for

基本信息

数据文档 查看数据文档
货号 PA10991
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human MAP3K5
特异性 Abundantly expressed in heart and pancreas.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q99683
浓度 1 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 Apoptosis signal regulating kinase 1,Apoptosis signal-regulating kinase 1,ASK 1,ASK-1,ASK1,M3K5,M3K5,MAP/ERK kinase kinase 5,MAP3K5,MAPK/ERK kinase kinase 5,MAPKKK5,MEK kinase 5,MEKK 5,MEKK5,Mitogen activated protein kinase kinase kinase 5,Mitogen-activated protein kinase kinase kinase 5
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

©2024 武汉天正源生物科技有限公司版权所有. SiteMap