Anti-Human/Mouse LRP6 Polyclonal Antibody

LRP6多克隆抗体

This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.
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基本信息

数据文档 查看数据文档
货号 PA07352
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human LRP6
特异性 Widely co-expressed with LRP5 during embryogenesis and in adult tissues.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot O75581
浓度 1.4 mg/mL
推荐稀释度 IHC 1:40-200, ELISA 1:2000-10000
配方
应用范围 IHC,ELISA
别名 ADCAD2,C030016K15Rik,Cd,FLJ90062,FLJ90421,LDL receptor related protein 6,Low density lipoprotein receptor related protein 6,Low-density lipoprotein receptor-related protein 6,LRP-6,LRP6,LRP6,OTTHUMP00000238979,OTTHUMP00000238980,OTTHUMP00000238982,STHAG7
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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