Anti-Human/Mouse IPO7 Polyclonal Antibody

IPO7多克隆抗体

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran's GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.
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基本信息

数据文档 查看数据文档
货号 PA10194
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human IPO7
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot O95373
浓度 0.5 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300
配方
应用范围 WB,IHC,ELISA
别名 FLJ14581,Imp 7,Imp7,Importin-7,Importin7,IPO 7,IPO7,IPO7,MGC138673,Ran binding protein 7,Ran-binding protein 7,RANBP 7,RanBP7
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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