Anti-Human /Mouse IL15RA Polyclonal Antibody

IL15RA多克隆抗体

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.
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基本信息

数据文档 查看数据文档
货号 PA03617
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human IL15RA
特异性 Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, isoform 7, isoform 8 and isoform 9 are widely expressed. Expressed in fetal brain with higher expression in the hippocampus and cerebellum than in cortex and thalamus. Higher levels of soluble sIL-15RA form in comparison with membrane-bound forms is present in all brain structures.
亚型 IgG
反应性 Human ,Mouse
克隆
Uniprot Q13261
浓度 0.5 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 AA690181,CD215,I15RA,IL 15R alpha,IL-15 receptor subunit alpha,IL-15R-alpha,IL-15RA,Il15ra,Interleukin 15 receptor alpha,Interleukin 15 receptor subunit alpha,MGC104179,sIL-15 receptor subunit alpha,sIL-15R-alpha,sIL-15RA,Soluble interleukin 15 receptor subunit alpha,Soluble interleukin-15 receptor subunit alpha
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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