Anti-Human/Mouse FGFR2 Polyclonal Antibody

FGFR2多克隆抗体

The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
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基本信息

数据文档 查看数据文档
货号 PA11296
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human FGFR2
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P21802
浓度 0.8 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 bacteria-expressed kinase,BBDS,BEK,BEK fibroblast growth factor receptor,BFR1,CD332,CD332 antigen,CEK3,CFD1,Craniofacial dysostosis 1,ECT1,FGF receptor,FGFR 2,FGFR-2,Fgfr2,FGFR2,Fibroblast growth factor receptor 2,Hydroxyaryl protein kinase,Jackson Weiss syndrome,JWS,K SAM,K-sam,Keratinocyte growth factor receptor 2,Keratinocyte growth factor receptor,KGFR,KSAM,protein tyrosine kinase,receptor like 14,soluble FGFR4 variant 4,TK14,TK25
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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