Anti-Human/Mouse FAM3B Polyclonal Antibody

FAM3B多克隆抗体

FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events. The gene encoding FAM3B maps to human chromosome 21, which houses approximately 300 genes and comprises nearly 1.5% of the human genome.
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基本信息

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货号 PA09450
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human FAM3B
特异性 Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P58499
浓度 0.7 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 2-21,C21orf11,C21orf76,Cytokine like protein 2 21,Cytokine-like protein 2-21,Fam3b,FAM3B,Family with sequence similarity 3 member B,ORF9,Pancreatic-derived factor,PANDER,PRED44,Protein FAM3B
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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