Anti-Human/Mouse ELF5 Polyclonal Antibody

ELF5多克隆抗体

The protein encoded by this gene is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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基本信息

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货号 PA03722
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human Elf-5
特异性 Expressed exclusively in tissues with a high content of epithelial cells. Highly expressed in salivary gland, mammary gland, kidney and prostate. Weakly expressed in placenta and lung. Isoform 1 and isoform 2 are differentially expressed in different tissues. In the kidney, only isoform 1 was expressed, while prostate expressed both isoforms, with levels of isoform 2 being higher. Expression is up-regulated during keratinocyte differentiation. Several epithelial carcinoma cell lines showed lack of expression.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9UKW6
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IF,ELISA
别名 E74 like factor 5 (ets domain transcription factor),E74 like factor 5,E74-like factor 5,ELF 5,ELF5,ELF5,Epithelium restricted ESE 1 related Ets factor,Epithelium restricted ESE1 related Ets factor,Epithelium specific Ets transcription factor 2,Epithelium-restricted ESE-1-related Ets factor,Epithelium-specific Ets transcription factor 2,ESE 2,ESE-2,ESE2,Ets domain TF,Ets domain transcription factor,ETS related transcription factor Elf 5,ETS related transcription factor Elf5,ETS-related transcription factor Elf-5
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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