Anti-Human/Mouse DUSP8 Polyclonal Antibody

DUSP8多克隆抗体

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin.
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基本信息

数据文档 查看数据文档
货号 PA11308
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human DUSP8
特异性 Abundant in brain, heart and skeletal muscle.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q13202
浓度 0.6 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 C11orf81,Chromosome 11 open reading frame 81,Deubiquitinating enzyme 8,Dual Specificity Phosphatase 8,Dual specificity phosphatase M3/6,Dual specificity protein phosphatase 8,Dual specificity protein phosphatase hVH 5,Dual specificity protein phosphatase hVH-5,DUS8,DUS8,DUSP8,EC 3.1.3.16,EC 3.1.3.48,FLJ42476,FLJ42958,H1 phosphatase vaccinia virus homolog,H1 phosphatase,vaccinia virus,homolog of,HB5,hUBPy,HVH5,HVH8,M3/6,mouse,homolog of,Neuronal tyrosine threonine phosphatase 1,Serine/threonine specific protein phosphatase,Ubiquitin carboxyl terminal hydrolase 8,Ubiquitin specific processing protease 8,Ubiquitin thiolesterase 8,VH5
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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