Anti-Human/Mouse DTX2 Polyclonal Antibody

DTX2多克隆抗体

DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
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基本信息

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货号 PA06823
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human DTX2
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q86UW9
浓度 0.5 mg/mL
推荐稀释度 IHC 1:10-1:50
配方
应用范围 IHC,ELISA
别名 Deltex 2,deltex homolog 2 (Drosophila),deltex,Drosophila,homolog of,2,Deltex2,DTX2,DTX2,hDTX2,Highly similar to hPMSR6 [H.sapiens],KIAA1528,Probable E3 ubiquitin-protein ligase DTX2,Protein deltex 2,Protein deltex-2,RING finger protein 58,RNF58,Zinc ion binding protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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