Anti-Human/Mouse DOC1 Polyclonal Antibody

DOC1多克隆抗体

The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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基本信息

数据文档 查看数据文档
货号 PA03564
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human DOC-1
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot O14519
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:5000
配方
应用范围 WB,ELISA
别名 CDK2 A1,CDK2 associated protein 1,CDK2-associated protein 1,CDK2AP1,CDKA1,CDKA1,Cyclin dependent kinase 2 associated protein 1,Cyclin-dependent kinase 2-associated protein 1,Deleted in oral cancer 1,DOC 1,DOC 1 related protein,DOC 1R,DOC-1,DOC1,DOC1R,DORC1,p12DOC 1,Putative oral cancer suppressor,ST19
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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