The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.CUX1 (Cut Like Homeobox 1) is a Protein Coding gene. Diseases associated with CUX1 include Fiedler's Myocarditis and Dirofilariasis. Among its related pathways are Intra-Golgi traffic and FGFR1 mutant receptor activation. GO annotations related to this gene include sequence-specific DNA binding and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is CUX2.