Carboxypeptidases have functions ranging from digestion of food to selective biosynthesis of neuroendocrine peptides. Members of the A/B subfamily of carboxypeptidases, such as CPA5, contain an approximately 90-amino acid pro region that assists in the folding of the active carboxypeptidase domain. Cleavage of the pro region activates the enzyme.CPA5 (Carboxypeptidase A5) is a Protein Coding gene. Diseases associated with CPA5 include Amebiasis and Silver-Russell Syndrome. GO annotations related to this gene include peptidase activity and carboxypeptidase activity. An important paralog of this gene is CPA1.