Anti-Human/Mouse CD42b Polyclonal Antibody

CD42b多克隆抗体

Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
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基本信息

数据文档 查看数据文档
货号 PA09642
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human GP1BA
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P07359
浓度 0.8 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300
配方
应用范围 WB,IHC,ELISA
别名 Antigen CD42b alpha,BDPLT1,BDPLT3,BSS,CD 42b,CD42b alpha,CD42B,CD42b antigen,DBPLT3,GLYCOCALICIN,Glycoprotein Ib (platelet) alpha polypeptide,Glycoprotein Ibalpha,GP Ib alpha,GP1B,GP1BA,GPIb alpha,GPIbA,MGC34595,Platelet glycoprotein Ib alpha chain,Platelet glycoprotein Ib alpha polypeptide,Platelet membrane glycoprotein 1b alpha subunit,VWDP
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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