Anti-Human/Mouse BMPR2 Polyclonal Antibody

BMPR2多克隆抗体

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
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基本信息

数据文档 查看数据文档
货号 PA12852
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human BMPR2
特异性 Highly expressed in heart and liver.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q13873
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 BMP type II receptor,BMP type-2 receptor,BMPR 2,BMPR 3,BMPR II,BMPR-2,BMPR-II,Bmpr2,BMPR2,BMPR3,BMPRII,BMR 2,BMR2,Bone morphogenetic protein receptor type 2,Bone morphogenetic protein receptor type II,Bone morphogenetic protein receptor type-2,Bone morphogenic protein receptor type II serine threonine kinase,BRK 3,BRK3,PPH 1,PPH1,Serine threonine kinase type II activin receptor like kinase,T ALK,TALK,Type II activin receptor like kinase
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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