AVPR1A (Arginine Vasopressin Receptor 1A) is a Protein Coding gene. Diseases associated with AVPR1A include Acth-Independent Macronodular Adrenal Hyperplasia and Asperger Syndrome. Among its related pathways are Peptide ligand-binding receptors and Vascular smooth muscle contraction. GO annotations related to this gene include G-protein coupled receptor activity and protein kinase C binding. An important paralog of this gene is AVPR1B.The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1B, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor mediates cell contraction and proliferation, platelet aggregation, release of coagulation factor and glycogenolysis.