Anti-Human/Mouse ATF1 Polyclonal Antibody

ATF1多克隆抗体

This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
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基本信息

数据文档 查看数据文档
货号 PA02166
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human ATF-1 around the non-phosphorylation site of Ser63.
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P18846
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
配方
应用范围 WB,IHC-p,ELISA
别名 Activating transcription factor 1,ATF 1,atf1,ATF1 EWS fusion gene,ATF1 FUS fusion gene,ATF1,cAMP dependent transcription factor 1,cAMP-dependent transcription factor ATF-1,Cyclic AMP dependent transcription factor ATF 1,Cyclic AMP dependent transcription factor ATF1,Cyclic AMP-dependent transcription factor ATF-1,EWS AFT1,FUS ATF 1,FUS/ATF 1,Protein TREB36,RNA binding protein activating transcription factor 1 fusion protein,TREB 36,TREB36,TREB36 protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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