Anti-Human/Mouse ASPN Polyclonal Antibody

ASPN多克隆抗体

This gene encodes a cartilage extracellular protein that is member of the small leucine-rich proteoglycan family. The encoded protein may regulate chondrogenesis by inhibiting transforming growth factor-beta 1-induced gene expression in cartilage. This protein also binds collagen and calcium and may induce collagen mineralization. Polymorphisms in the aspartic acid repeat region of this gene are associated with a susceptibility to osteoarthritis. Alternate splicing results in multiple transcript variants.
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基本信息

数据文档 查看数据文档
货号 PA09375
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human ASPN
特异性 Higher levels in osteoarthritic articular cartilage, aorta, uterus. Moderate expression in small intestine, heart, liver, bladder, ovary, stomach, and in the adrenal, thyroid, and mammary glands. Low expression in trachea, bone marrow, and lung. Co-localizes with TGFB1 in chondrocytes within osteoarthritic (OA) lesions of articular cartilage.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9BXN1
浓度 0.6 mg/mL
推荐稀释度 WB 1:500-1:2000
配方
应用范围 WB,ELISA
别名 ASPN,ASPN protein,ASPN,Asporin (LRR class 1),Asporin,Asporin proteoglycan,FLJ20129,LRR class 1,Periodontal ligament associated protein 1,Periodontal ligament-associated protein 1,PLAP 1,PLAP-1,PLAP1,SLRR 1C,SLRR1C,Small leucine rich protein 1C
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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