Anti-Human/Mouse ARID1A Polyclonal Antibody

ARID1A多克隆抗体

This gene encodes a member of the SWI/SNF family, whose members have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. It possesses at least two conserved domains that could be important for its function. First, it has a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. Second, the C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that the protein encoded by this gene confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions. 
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基本信息

数据文档 查看数据文档
货号 PA09203
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human ARID1A
特异性 Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL, and at a much lower level in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot O14497
浓度 0.6 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 actin-dependent regulator of chromatin subfamily F member 1,ARI1A,ARID domain containing protein 1A,ARID domain-containing protein 1A,ARID1A,AT rich interactive domain 1A (SWI like),AT rich interactive domain 1A,AT rich interactive domain containing protein 1A,AT-rich interactive domain-containing protein 1A,B120,BAF250,BAF250A,BM029,brain protein 120,BRG1 associated factor 250,BRG1 associated factor 250a,BRG1-associated factor 250,BRG1-associated factor 250a,C1ORF4,chromatin remodeling factor p250,chromosome 1 open reading frame 4,ELD,hELD,hOSA1,matrix-associated,MRD14,Osa homolog 1,OSA1,OSA1 nuclear protein,P270,SMARCF1,SWI like protein,SWI SNF complex protein p270,SWI-like protein,SWI/SNF complex protein p270,SWI/SNF related,matrix associated,actin dependent regulator of chromatin,subfamily f,member 1,SWI/SNF-related
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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