Anti-Human/Mouse ARC Polyclonal Antibody

ARC多克隆抗体

Arc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
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基本信息

数据文档 查看数据文档
货号 PA12927
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human ARC
特异性
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q7LC44
浓度 0.4 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 activity regulated cytoskeleton associated protein,activity regulated gene 3.1 protein homolog,Activity-regulated cytoskeleton-associated protein,Activity-regulated gene 3.1 protein homolog,Arc,ARC/ARG3.1,ARC,Arg3.1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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