Anti-Human/Mouse ALKBH1 Polyclonal Antibody

ALKBH1多克隆抗体

This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It is involved in damage reversal by oxidative demethylation of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate and iron. May have a role in placental trophoblast lineage differentiation. Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single-stranded DNA and double-stranded DNA at abasic sites, with the greatest activity towards double-stranded DNA with two abasic sites.
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基本信息

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货号 PA12871
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human ALKBH1
特异性 Ubiquitous.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q13686
浓度 0.2 mg/mL
推荐稀释度 WB 1:200-1:1000
配方
应用范围 WB,ELISA
别名 ABH,ABH1,alkB,alkB homolog 1 histone H2A dioxygenase,AlkB,alkylation repair homolog 1 (E. coli),ALKB1,ALKBH,ALKBH1,Alkylated DNA repair protein alkB homolog 1,Alkylation repair homolog 1,Alkylation repair,alkB homolog,Alpha-ketoglutarate-dependent dioxygenase ABH1,DNA lyase ABH1,DNA oxidative demethylase ALKBH1,hABH
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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