Anti-Human/Monkey DR4 Polyclonal Antibody

DR4多克隆抗体

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. 
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基本信息

数据文档 查看数据文档
货号 PA03589
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human DR4
特异性 Widely expressed. High levels are found in spleen, peripheral blood leukocytes, small intestine and thymus, but also in K562 erythroleukemia cells, MCF7 breast carcinoma cells and activated T-cells.
亚型 IgG
反应性 Human,Monkey
克隆
Uniprot O00220
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:100-1:300, ELISA 1:5000
配方
应用范围 WB,IF,ELISA
别名 Apo2,CD261,Cytotoxic TRAIL receptor,Death receptor 4,DR4,NF related apoptosis-inducing ligand receptor 1,TNF receptor superfamily member 10a,TNF-related apoptosis-inducing ligand receptor 1,TNFRSF10A,TR10A,TRAIL receptor 1,TRAIL-R1,TRAILR 1,TRAILR1,Tumor necrosis factor receptor superfamily member 10A,Tumor necrosis factor receptor superfamily member 10a variant 2,Tumor necrosis factor receptor superfamily,member 10a
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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