Anti-Human MMP8 Polyclonal Antibody

MMP8多克隆抗体

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
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基本信息

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货号 PA10958
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human MMP8
特异性 Neutrophils.
亚型 IgG
反应性 Human
克隆
Uniprot P22894
浓度 0.4 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 CLG 1,CLG1,Collagenase 1,Collagenase 1 neutrophil,HNC,Matrix metallopeptidase 8 (neutrophil collagenase),Matrix metalloprotease 8,Matrix metalloproteinase-8,MMP 8,MMP-8,Mmp8,MMP8,Neutrophil collagenase,PMNL CL,PMNL collagenase,PMNL-CL,PMNLCL
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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