The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes a protein which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.MGST2 (Microsomal Glutathione S-Transferase 2) is a Protein Coding gene. Among its related pathways are Platinum drug resistance and Glutathione metabolism. GO annotations related to this gene include enzyme activator activity and glutathione peroxidase activity. An important paralog of this gene is LTC4S.