Anti-Human LIN28B Polyclonal Antibody

LIN28B多克隆抗体

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]
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基本信息

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货号 PA09897
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human LIN28B
特异性 High expression in testis, fetal liver, placenta and in hepatocellular carcinoma (HCC). Isoform 1 is only detected in moderately and poorly differentiated HCC tissues and placenta (at protein level). Isoform 2 is detected in fetal liver, non-tumor liver tissues, as well as well-differentiated tumor tissues (at protein level).
亚型 IgG
反应性 Human
克隆
Uniprot Q6ZN17
浓度 0.3 mg/mL
推荐稀释度 WB 1:500-1:2000
配方
应用范围 WB,ELISA
别名 CSDD 2,CSDD2,FLJ16517,Lin 28 homolog B (C. elegans),Lin 28.2,Lin-28B,LIN28B,LN28B,Protein lin-28 homolog B
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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