Anti-Human KISS1R Polyclonal Antibody

KISS1R多克隆抗体

The protein encoded by this gene is a galanin-like G protein-coupled receptor that binds metastin, a peptide encoded by the metastasis suppressor gene KISS1. The tissue distribution of the expressed gene suggests that it is involved in the regulation of endocrine function, and this is supported by the finding that this gene appears to play a role in the onset of puberty. Mutations in this gene have been associated with hypogonadotropic hypogonadism and central precocious puberty.
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基本信息

数据文档 查看数据文档
货号 PA10285
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human KISS1R
特异性 Most highly expressed in the pancreas, placenta and spinal cord, with lower-level of expression in peripheral blood leukocytes, kidney, lung, fetal liver, stomach, small intestine, testes, spleen, thymus, adrenal glands and lymph nodes. In the adult brain, expressed in the superior frontal gyrus, putamen, caudate nucleus, cingulate gyrus, nucleus accumbens, hippocampus, pons and amygdala, as well as the hypothalamus and pituitary. Expression levels are higher in early (7-9 weeks) than term placentas. Expression levels were increased in both early placentas and molar pregnancies and were reduced in choriocarcinoma cells. Expressed at higher levels in first trimester trophoblasts than at term of gestation. Also found in the extravillous trophoblast suggesting endocrine/paracrine activation mechanism.
亚型 IgG
反应性 Human
克隆
Uniprot Q969F8
浓度 #N/A
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 AXOR 12,AXOR12,G protein coupled receptor 54,G-protein coupled receptor 54,G-protein coupled receptor OT7T175,GPCR 54,GPCR54,GPR 54,GPR54,hOT7T175,Hypogonadotropin 1,Hypogonadotropin-1,Hypogonadotropin1,KISS 1 receptor,KISS 1R,KiSS-1 receptor,KiSS-1R,KISS1 receptor,Kiss1r,Kisspeptins receptor,KISSR,Metastin receptor,OT7T175
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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