Anti-Human JTB Polyclonal Antibody

JTB多克隆抗体

Required for normal cytokinesis during mitosis. Plays a role in the regulation of cell proliferation. May be a component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Increases AURKB activity. Inhibits apoptosis induced by TGFB1 (By similarity). Overexpression induces swelling of mitochondria and reduces mitochondrial membrane potential.
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基本信息

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货号 PA05813
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the N-terminal region of human JTB
特异性 Ubiquitous. Expressed in all normal human tissues studied but overexpressed or underexpressed in many of their malignant counterparts.
亚型 IgG
反应性 Human
克隆
Uniprot O76095
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:5000
配方
应用范围 WB,ELISA
别名 hJT,HJTB,HSPC222,JTB,JTB,Jumping translocation breakpoint,Jumping translocation breakpoint protein,OTTHUMP00000034759,PAR,PAR protein,Prostate androgen regulated protein,Prostate androgen-regulated protein,Protein JTB
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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