Anti-Human FGR Polyclonal Antibody

FGR多克隆抗体

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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基本信息

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货号 PA02696
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human c-Fgr around the non-phosphorylation site of Y412.
特异性 Detected in neutrophils, monocytes and natural killer cells (at protein level). Detected in monocytes and large lymphocytes.
亚型 IgG
反应性 Human
克隆
Uniprot P09769
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
配方
应用范围 WB,IHC-p,ELISA
别名 c fgr,c fgr protooncogene,c src 2 proto oncogene,c src2,Fgr,FGR,FLJ43153,Gardner Rasheed feline sarcoma viral (v fgr),Gardner Rasheed feline sarcoma viral (v fgr) oncogene homolog,Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog,MGC75096,p55 c fgr protein,P55 FGR,P55-FGR,p55c fgr,p58-Fgr,p58c fgr,p58c-Fgr,Proto oncogene c Fgr,Proto oncogene tyrosine protein kinase FGR,Proto-oncogene c-Fgr,SRC 2,SRC2,Tyrosine protein kinase Fgr,Tyrosine-protein kinase Fgr
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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