Anti-Human FAIM3 Polyclonal Antibody

FAIM3多克隆抗体

Fc receptors specifically bind to the Fc region of immunoglobulins (Igs) to mediate the unique functions of each Ig class. FAIM3 encodes an Fc receptor for IgM. May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream.
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基本信息

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货号 PA09438
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human FAIM3
特异性 Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat cells, CemT4 cells, MolT-4 cells, HB11.19 cells, and Reh cells. No expression detected in nonhematopoietic cell lines, including HepG2 cells, 293 cells and Hela cells.
亚型 IgG
反应性 Human
克隆
Uniprot O60667
浓度 0.2 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:20-1:100
配方
应用范围 WB,IHC,ELISA
别名 Faim3,FAIM3,Fas apoptotic inhibitory molecule 3,Fc fragment of IgM receptor,Fc mu receptor,FCMR,IgM Fc receptor,Immunoglobulin mu Fc receptor,Regulator of Fas induced apoptosis,Regulator of Fas-induced apoptosis Toso,TOSO
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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