Anti-Human EIF2AK2 Polyclonal Antibody

EIF2AK2多克隆抗体

Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
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基本信息

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货号 PA05598
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human PKR around the non-phosphorylation site of T258.
特异性 Highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. Colocalizes with GSK3B and TAU in the Alzheimer disease (AD) brain. Elevated levels seen in breast and colon carcinomas,and which correlates with tumor progression and invasiveness or risk of progression.
亚型 IgG
反应性 Human
克隆
Uniprot P19525
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:40000
配方
应用范围 WB,IHC-p,ELISA
别名 Double stranded RNA activated protein kinase;,E2AK2,eIF-2A protein kinase 2,EIF2AK1,EIF2AK2,Eukaryotic translation initiation factor 2 alpha kinase 2,Eukaryotic translation initiation factor 2-alpha kinase 2,HGNC:9437,Interferon induced double stranded RNA activated protein kinase,Interferon inducible elF2 alpha kinase,Interferon inducible RNA dependent protein kinase,Interferon-induced,double-stranded RNA-activated protein kinase,Interferon-inducible RNA-dependent protein kinase,MGC126524,P1/eIF-2A protein kinase,P1/eIF2A protein kinase,p68 kinase,PKR,PPP1R83,PRKR,Protein kinase interferon inducible double stranded RNA dependent,Protein kinase RNA activated,Protein kinase RNA-activated,Protein phosphatase 1 regulatory subunit 83,Serine/threonine protein kinase TIK,Tyrosine protein kinase EIF2AK2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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