Anti-Human DNMT3L Polyclonal Antibody

DNMT3L多克隆抗体

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases, but is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, it does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA03652
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human DNMT3L
特异性 Expressed at low levels in several tissues including testis, ovary, and thymus.
亚型 IgG
反应性 Human
克隆
Uniprot Q9UJW3
浓度 0.2 mg/mL
推荐稀释度 IHC 1:10-1:50
配方
应用范围 IHC,ELISA
别名 Cytosine 5 methyltransferase 3 like protein,DNA (cytosine 5 ) methyltransferase 3 like,DNA (cytosine-5)-methyltransferase 3-like,DNA cytosine 5 methyltransferase 3 like protein,DNA methyltransferase 3 like protein,DNM3L,Dnmt 3L,Dnmt3l,Human cytosine 5 methyltransferase 3 like protein,MGC1090
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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