Anti-Human CMKLR1 Polyclonal Antibody

CMKLR1多克隆抗体

Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).
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基本信息

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货号 PA02770
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CMKLR1
特异性 Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.
亚型 IgG
反应性 Human
克隆
Uniprot Q99788
浓度 1 mg/mL
推荐稀释度 IHC 1:25-100, ELISA 1:2000-5000
配方
应用范围 IHC,ELISA
别名 CHEMERINR,Chemokine like receptor 1,Chemokine-like receptor 1,CHEMR23,CMKLR1,CML1,DEZ,G protein coupled receptor ChemR23,G protein coupled receptor DEZ,G-protein coupled receptor ChemR23,G-protein coupled receptor DEZ,Orphan G protein coupled receptor,Orphan G protein coupled receptor Dez,Resolvin E1 receptor,RVER1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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