Anti-Human Claudin 8 Polyclonal Antibody

Claudin 8多克隆抗体

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellular cation barrier of the distal renal tubule, and in the paracellular barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma.
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基本信息

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货号 PA11222
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CLDN8
特异性 Expressed in the epididymis, mainly in the caput segment.
亚型 IgG
反应性 Human
克隆
Uniprot P56748
浓度 0.5 mg/mL
推荐稀释度 IHC 1:100-1:300
配方
应用范围 IHC,ELISA
别名 Claudin 8,Claudin-8,CLD8,Cldn8,Epididymis secretory protein Li 79,HEL S 79,OTTHUMP00000101915
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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