Anti-Human CD307 Polyclonal Antibody

CD307多克隆抗体

This gene encodes a member of the immunoglobulin receptor superfamily and the Fc-receptor like family. This gene and several other Fc receptor-like gene members are clustered on the long arm of chromosome 1. The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains. This gene is implicated in B cell development and lymphomagenesis. Alternatively spliced transcript variants encoding different isoforms have been identified.FCRL5 (Fc Receptor Like 5) is a Protein Coding gene. Diseases associated with FCRL5 include Hairy Cell Leukemia and Burkitt Lymphoma. An important paralog of this gene is FCRL3.
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基本信息

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货号 PA06410
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human CD307.
特异性 Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detected in lymph node, spleen, bone marrow, and small intestine with preponderance of isoform 3. Expressed in mature and memory B cells and down-regulated in germinal center cells (at protein level).
亚型 IgG
反应性 Human
克隆
Uniprot Q96RD9
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 BXMAS1,CD307 antigen,CD307e,Fc receptor homolog 5,Fc receptor like 5,Fc receptor-like protein 5,FcR-like protein 5,FcRH5,FcRL5,FCRL5,Immune receptor translocation-associated protein 2,Immunoglobulin receptor translocation associated gene 2 protein,Immunoglobulin superfamily receptor translocation associated gene 2 protein,IRTA2,UNQ503/PRO820
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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