Anti-Human CD1C Polyclonal Antibody

CD1C多克隆抗体

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.CD1C (CD1c Molecule) is a Protein Coding gene. Diseases associated with CD1C include Mycobacterium Malmoense and Foramen Magnum Meningioma. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Innate Immune System. GO annotations related to this gene include beta-2-microglobulin binding and lipopeptide binding. An important paralog of this gene is CD1B.
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基本信息

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货号 PA06385
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human CD1C.
特异性 Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
亚型 IgG
反应性 Human
克隆
Uniprot P29017
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:20000
配方
应用范围 WB,ELISA
别名 BDCA1,CD1,CD1A,CD1c,CD1c antigen,CD1C antigen c polypeptide,CD1c molecule,CD1C,Cortical thymocyte antigen CD1C,Differentiation antigen CD1 alpha 3,R7,T cell surface glycoprotein CD1c,T-cell surface glycoprotein CD1c
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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