Anti-Human CD163 Polyclonal Antibody

CD163多克隆抗体

The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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基本信息

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货号 PA10454
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CD163
特异性 Expressed in monocytes and mature macrophages such as Kupffer cells in the liver, red pulp macrophages in the spleen, cortical macrophages in the thymus, resident bone marrow macrophages and meningeal macrophages of the central nervous system. Expressed also in blood. Isoform 1 is the lowest abundant in the blood. Isoform 2 is the lowest abundant in the liver and the spleen. Isoform 3 is the predominant isoform detected in the blood.
亚型 IgG
反应性 Human
克隆
Uniprot Q86VB7
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 C163A,CD 163,CD163,CD163 antigen,CD163 molecule,Hemoglobin scavenger receptor,M130,M130 antigen precursor,Macrophage associated antigen,MM130,OTTHUMP00000238617,OTTHUMP00000238618,OTTHUMP00000238619,OTTHUMP00000238620,SCARI1,Scavenger receptor cysteine rich type 1 protein M130,sCD163,Soluble CD163
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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